Ethyl (R)-(-)-2-pyrrolidone-5-carboxylate - Names and Identifiers
Name | Ethyl D-(-)-pyroglutamate
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Synonyms | H-D-Pyr-OEt Ethyl D-pyroglutamate ethyl 5-oxo-D-prolinate Ethyl D-(-)-pyroglutamate D-Pyroglutamic ethyl ester D-(-)-Pyroglutamic acid ethyl ester Ethyl (R)-(-)-2-pyrrolidone-5-carboxylate (R)-5-Oxo-2-pyrrolidinecarboxylic acid ethyl ester (2R)-5-Oxo-2β-pyrrolidinecarboxylic acid ethyl ester (R)-5-Oxoproline ethyl ester, D-5-Oxo-2-pyrrolidinecarboxylic acid ethyl ester Ethyl (R)-(-)-2-pyrrolidone-5-carboxylateD(-)-Pyroglutamic acid ethyl esterEthyl (R)-(-)-pyroglutamateEthyl D(-)-pyroglutamate (R)-5-Oxoproline ethyl ester, D-5-Oxo-2-pyrrolidinecarboxylic acid ethyl ester, D-Pyroglutamic acid ethyl ester, Ethyl 5-oxo-D-proline, Ethyl pyroglutamate
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CAS | 68766-96-1
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InChI | InChI=1/C7H11NO3/c1-2-11-7(10)5-3-4-6(9)8-5/h5H,2-4H2,1H3,(H,8,9)/t5-/m1/s1 |
Ethyl (R)-(-)-2-pyrrolidone-5-carboxylate - Physico-chemical Properties
Molecular Formula | C7H11NO3
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Molar Mass | 157.17 |
Density | 1.2483 (rough estimate) |
Melting Point | 53-57°C |
Boling Point | 176°C12mm Hg(lit.) |
Specific Rotation(α) | 3.5 º (C=5, H2O) |
Flash Point | >230°F |
Solubility | Chloroform (Slightly), Methanol (Slightly) |
Vapor Presure | 0.000519mmHg at 25°C |
Appearance | Crystalline powder |
Color | White to Light Brown Low-Melting |
BRN | 82622 |
pKa | 14.78±0.40(Predicted) |
Storage Condition | Sealed in dry,2-8°C |
Refractive Index | n20/D 1.478(lit.) |
MDL | MFCD00010848 |
Physical and Chemical Properties | alpha:3.5 o (c=5, H2O) |
Ethyl (R)-(-)-2-pyrrolidone-5-carboxylate - Risk and Safety
Hazard Symbols | Xi - Irritant
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Risk Codes | 36/37/38 - Irritating to eyes, respiratory system and skin.
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Safety Description | S37/39 - Wear suitable gloves and eye/face protection
S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
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WGK Germany | 3 |
FLUKA BRAND F CODES | 3-10 |
HS Code | 29337900 |
Ethyl (R)-(-)-2-pyrrolidone-5-carboxylate - Introduction
Ethyl D-(-)-pyroglutamate(Ethyl D-(-)-pyroglutamate) is an organic compound with the formula C7H11NO3. It is a white or almost white crystalline solid, soluble in alcohol and ketone solvents, insoluble in water.
Ethyl D-(-)-pyroglutamate has a wide range of applications in the fields of medicine, biological science and chemical research. It is often used as a non-natural amino acid for the synthesis of biologically active molecules and drug development. It is also used as an antioxidant, capable of reducing oxidative stress and damage to cells. In addition, Ethyl D-(-)-pyroglutamate is also used in the breeding industry, which can improve the growth performance and immune function of animals.
The method for preparing Ethyl D-(-)-pyroglutamate usually includes reacting pyroglutamic acid with ethanol, and obtaining the product through esterification. Specifically, pyroglutamic acid can be reacted with ethyl acetate under alkaline conditions and subjected to crystallization and purification to obtain the target product.
Regarding safety information, Ethyl D-(-)-pyroglutamate has no obvious hazards under normal use conditions. However, in handling and use, general laboratory practices should be followed and direct contact with skin and eyes should be avoided. In addition, it should be stored in a sealed container, away from fire and oxidizing agents. In case of accidental inhalation or contact, seek medical attention immediately. For detailed safety information, please refer to the safety data sheet provided by the supplier.
Last Update:2024-04-09 20:52:54